You will find a release of norepinephrine in the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors in the dorsal horn to lower afferent discomfort transmission and develop analgesia. For that reason, drugs like clonidine that concentrate on alpha-2 receptors can affect the transmission of discomfort. Intense Allergic Reactions. https://stanleyi384asi0.vigilwiki.com/user