While in the LSD-certain crystal structure, the side chain in the lid residue L209EL2 types extensive hydrophobic contacts with each LSD and surrounding residues in TMs III, IV, and V (Figure 4C). Once the lid moved aside to reveal the binding pocket in simulation, several of those contacts broke. We https://lsdaztec9994690.bloggin-ads.com/58302724/lsd-crystal-for-dummies